Higher Concentrations of Alanine Aminotransferase within the Reference Interval Predict Nonalcoholic Fatty Liver Disease
نویسندگان
چکیده
منابع مشابه
Higher concentrations of alanine aminotransferase within the reference interval predict nonalcoholic fatty liver disease.
BACKGROUND In nonalcoholic fatty liver disease (NAFLD), increased alanine aminotransferase (ALT) concentrations are considered to be a consequence of hepatocyte damage. We performed a prospective study to examine the association between ALT within its reference interval and risk for subsequent development of NAFLD. METHODS The study cohort comprised 5237 healthy men without diagnosed NAFLD an...
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Nonalcoholic fatty liver disease (NAFLD) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. So changing in life style and interventions on obesogenic environment is cornerstone of NAFLD therapy in obese children. Some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...
متن کاملAlanine aminotransferase as an independent predictor of incident nonalcoholic fatty liver disease.
To the Editor: We read with interest the recent article by Chang et al. (1 ) reporting that higher serum alanine aminotransferase (ALT) concentrations, within the reference interval, independently predicted the incidence of nonalcoholic fatty liver disease (NAFLD) during a mean follow-up of 2.5 years in a large cohort of apparently healthy Korean men. Several prospective studies have previously...
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متن کاملClinical significance of serum alanine aminotransferase and lifestyle intervention in children with nonalcoholic fatty liver disease
PURPOSE This study aimed to investigate the clinical significance of serum alanine aminotransferase (ALT) levels in children with nonalcoholic fatty liver disease (NAFLD) and the effect of lifestyle intervention on NAFLD. METHODS The clinical data of 86 children diagnosed with NAFLD were reviewed retrospectively. Forty-six patients belonged to the elevated ALT group and 40 to the normal ALT g...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2007
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2006.081257